Microfluidic Microcirculation Mimetic for Exploring Biophysical Mechanisms of Chemotherapy-Induced Metastasis

A. Abraham, S. Virdi, Nick Herrero, Israel Bryant, Chisom Nwakama, Megha Jacob, Gargee Khaparde, Destiny Jordan, Mackenzie McCuddin, Spencer Mckinley, Adam Taylor, Conner Peeples, Andrew E. Ekpenyong

Micromachines, 2023

Simulated Microgravity-Induced Changes to Drug Response in Cancer Cells Quantified Using Fluorescence Morphometry

Spencer Mckinley, Adam Taylor, Conner Peeples, Megha Jacob, Gargee Khaparde, Yohan Walter, Andrew E. Ekpenyong

Life, 2023

Fractional calculus modeling of cell viscoelasticity quantifies drug response and maturation more robustly than integer order models

Anh Vo, Andrew E. Ekpenyong

2022

The role of cell mechanics in chemotherapy-induced metastasis

S. Virdi, N. Herrero, Israel Bryant, Destiny Jordan, A. Abraham, Gargee Khaparde, Megha Jacob, Chisom Nwakama, Andrew E. Ekpenyong

Biophysical Journal, 2022

Development of In Vitro Assays for Advancing Radioimmunotherapy against Brain Tumors

Yohan Walter, A. Hubbard, Allie Benoit, Erika A. Jank, Olivia Salas, Destiny Jordan, Andrew E. Ekpenyong

Biomedicines, 2022

Which Chemotherapy Drugs Alter Cell Mechanical Properties with Impact on Metastasis?

A. Abraham, Mackenzie McCuddin, Chisom Nwakama, Megha Jacob, Gargee Khaparde, S. Baumel, Spencer Mckinley, John F. Lewison, S. Virdi, Destiny Jordan, Harry Kramer, Andrew E. Ekpenyong

2021

Mathematical Physics for Nuclear Experiments

Andrew E. Ekpenyong

2021

Energy Loss of Electrons and Positrons through Matter

Andrew E. Ekpenyong

Mathematical Physics for Nuclear Experiments, 2021

Radioactivity and Decay Law

Andrew E. Ekpenyong

Mathematical Physics for Nuclear Experiments, 2021

Probability and Statistics for Nuclear Experimental Data

Andrew E. Ekpenyong

Mathematical Physics for Nuclear Experiments, 2021

Interactions of Photons in Matter

Andrew E. Ekpenyong

Mathematical Physics for Nuclear Experiments, 2021

Energy Loss of Heavy Charged Particles through Matter

Andrew E. Ekpenyong

Mathematical Physics for Nuclear Experiments, 2021

Private sector initiatives to tackle the burden of COVID-19: experiences from the Nigerian frontline

A. Otu, E. Effa, V. Umoh, N. Maxwell, Andrew E. Ekpenyong

The Pan African Medical Journal, 2021

Novel Curcumin-Resveratrol Solid Nanoparticles Synergistically Inhibit Proliferation of Melanoma Cells

Gayathri Heenatigala Palliyage, N. Hussein, Michael J. Mimlitz, Catherine Weeder, Marya Hassan A Alnasser, Somnath Singh, Andrew E. Ekpenyong, A. Tiwari, Harsh Chauhan

Pharmaceutical Research, 2021

In vitro radiotherapy and chemotherapy alter migration of brain cancer cells before cell death

Michael Merrick, Michael J. Mimlitz, Catherine Weeder, Haris Akhter, A. Bray, A. Walther, Chisom Nwakama, Joe Bamesberger, H. Djam, Kaamil Abid, Andrew E. Ekpenyong

Biochemistry and Biophysics Reports, 2021

Quantum Dots for Assessment of Reactive Oxygen Species Accumulation During Chemotherapy and Radiotherapy.

K. Djam, B. Lee, Sindhuja Suresh, Andrew E. Ekpenyong

Methods in molecular biology, 2020

Prevalence of IgG and IgM antibodies to SARS-CoV-2 among clinic staff and patients

M. Asuquo, E. Effa, A. Otu, O. Ita, Ubong A. Udoh, V. Umoh, O. Gbotosho, A. Ikpeme, S. Ameh, William O Egbe, Margaret Etok, J. Guck, Andrew E. Ekpenyong

medRxiv, 2020

Radiotherapy and chemotherapy alter migration of brain cancer cells before cell death

Michael Merrick, Michael J. Mimlitz, Catherine Weeder, Haris Akhter, A. Bray, A. Walther, Chisom Nwakama, Joe Bamesberger, H. Djam, Kaamil Abid, Andrew E. Ekpenyong

bioRxiv, 2020

Microgravity Modulates Effects of Chemotherapeutic Drugs on Cancer Cell Migration

Devika Prasanth, Sindhuja Suresh, Sruti Prathivadhi-Bhayankaram, Michael J. Mimlitz, Noah Zetocha, B. Lee, Andrew E. Ekpenyong

bioRxiv, 2019

RISK FACTORS FOR CARDIOVASCULAR EVENTS IN RURAL NIGERIA: A CROSS SECTIONAL SURVEY AND A REVIEW OF THE CURRENT LITERATURE

N. Ani, Edoise M. Isiwele, Andrew E. Ekpenyong, E. Ekanem, Anthonia A Ikpeme

Innovative Journal of Medical and Health Science, 2019

Effects of Ionizing Radiation on the Mechanosensitivity of Single Cells

Andrew E. Ekpenyong, Michael J. Mimlitz, Noah Zetocha, Kaamil Abid, B. Lee

2018

Optoelectronic Tuning of Quantum Dots by Biological Cells

B. Lee, Sindhuja Suresh, Andrew E. Ekpenyong

2018

Fluorescence intensity modulation of CdSe/ZnS quantum dots assesses reactive oxygen species during chemotherapy and radiotherapy for cancer cells

B. Lee, Sindhuja Suresh, Andrew E. Ekpenyong

Journal of Biophotonics, 2018

Electric Impedance Monitoring of Cell Migration Following Irradiation

Christopher Landis, Michael J. Mimlitz, M. Correa, Noah Zetocha, Andrew E. Ekpenyong

2018

Refractive index measurements of single, spherical cells using digital holographic microscopy.

M. Schürmann, J. Scholze, P. Müller, C. J. Chan, Andrew E. Ekpenyong, K. Chalut, J. Guck

Methods in Cell Biology, 2018

A comparison of methods to assess cell mechanical properties

Pei-Hsun Wu, D. R. Aroush, A. Asnacios, Wei-Chiang Chen, M. Dokukin, B. Doss, P. Durand-Smet, Andrew E. Ekpenyong, J. Guck, N. Guz, P. Janmey, Jerry S. H. Lee, N. M. Moore, A. Ott, Y. Poh, R. Ros, M. Sander, I. Sokolov, J. Staunton, Ning Wang, G. Whyte, D. Wirtz

Nature Methods, 2018

The Value of Mobile Ultrasound Services in Rural Communities in South-South Nigeria

A. Ikpeme, N. Ani, B. Ago, E. Effa, O. Kosoko-Lasaki, Andrew E. Ekpenyong

Open Access Macedonian Journal of Medical Sciences, 2017

Mechanical deformation induces depolarization of neutrophils

Andrew E. Ekpenyong, N. Toepfner, C. Fiddler, M. Herbig, Wenhong Li, G. Cojoc, C. Summers, J. Guck, E. Chilvers

Science Advances, 2017

Cyto-molecular Tuning of Quantum Dots

B. Lee, Sindhuja Suresh, Andrew E. Ekpenyong

2017

Microgravity Modulates Drug-Induced Enhancement of Cancer Cell Migration

Devika Prasanth, Sindhuja Suresh, Michael J. Mimlitz, Noah Zetocha, Andrew E. Ekpenyong

2017

Chemotherapy Impedes In Vitro Microcirculation and Promotes Migration of Leukemic Cells with Impact on Metastasis

Sruti Prathivadhi-Bhayankaram, Jianhao Ning, Michael J. Mimlitz, Carolyn Taylor, E. Gross, M. Nichols, J. Guck, Andrew E. Ekpenyong

2017

Effects of Chemotherapy-Induced Alterations in Cell Mechanical Properties on Cancer Metastasis

Sruti Prathivadhi, Andrew E. Ekpenyong, M. Nichols, Carolyn Taylor, Jianhao Ning

2016

Cell Mechanical Properties and Cancer Metastasis: Effects of Cancer Drugs and Radiotherapy

Sruti Prathivadhi-Bhayankaram, Carolyn Taylor, Jianhao Ning, M. Nichols, Andrew E. Ekpenyong

2016

Chemotherapy impedes in vitro microcirculation and promotes migration of leukemic cells with impact on metastasis.

Sruti Prathivadhi-Bhayankaram, Jianhao Ning, Michael J. Mimlitz, Carolyn Taylor, E. Gross, M. Nichols, J. Guck, Andrew E. Ekpenyong

Biochemical and Biophysical Research Communications - BBRC, 2016

Mechanotransduction in neutrophil activation and deactivation.

Andrew E. Ekpenyong, N. Toepfner, E. Chilvers, J. Guck

Biochimica et Biophysica Acta, 2015

Cell mechanics and immune system link up to fight infections

Andrew E. Ekpenyong, Si Ming Man, Panagiotis Tourlomousis, Sarra Achouri, Eugenia Cammarota, K. Hughes, A. Rizzo, Gilbert Ng, J. Guck, C. Bryant

2015

Myosin II Activity Softens Cells in Suspension.

C. J. Chan, Andrew E. Ekpenyong, Stefan Golfier, Wenhong Li, K. Chalut, O. Otto, J. Elgeti, J. Guck, F. Lautenschläger

Biophysical Journal, 2015

Real-time deformability cytometry: on-the-fly cell mechanical phenotyping

O. Otto, P. Rosendahl, Alexander Mietke, Stefan Golfier, C. Herold, D. Klaue, S. Girardo, S. Pagliara, Andrew E. Ekpenyong, A. Jacobi, M. Wobus, N. Töpfner, U. Keyser, J. Mansfeld, E. Fischer-Friedrich, J. Guck

Nature Methods, 2015

The Evolution of Mechanical Properties of Differentiating Stem Cells is Fate- and Function-Dependent

Andrew E. Ekpenyong, J. Guck

2014

Separation of blood cells with differing deformability using deterministic lateral displacement†

D. Holmes, G. Whyte, J. Bailey, Nuria Vergara-Irigaray, Andrew E. Ekpenyong, J. Guck, T. Duke

Interface Focus, 2014

Actin polymerization as a key innate immune effector mechanism to control Salmonella infection

Si Ming Man, Andrew E. Ekpenyong, Panagiotis Tourlomousis, Sarra Achouri, Eugenia Cammarota, K. Hughes, A. Rizzo, Gilbert Ng, John A. Wright, P. Cicuta, J. Guck, C. Bryant

Proceedings of the National Academy of Sciences of the United States of America, 2014

deterministic lateral displacement Separation of blood cells with differing deformability using

T. Duke, D. Holmes, G. Whyte, J. Bailey, Nuria Vergara-Irigaray, Andrew E. Ekpenyong, J. Guck

2014

Bacterial infection of macrophages induces decrease in refractive index

Andrew E. Ekpenyong, Si Ming Man, Sarra Achouri, C. Bryant, J. Guck, K. Chalut

Journal of Biophotonics, 2013

Elastic theory for the deformation of a solid or layered spheroid under axisymmetric loading

Lars Boyde, Andrew E. Ekpenyong, G. Whyte, J. Guck

2013

Viscoelastic Properties of Differentiating Blood Cells Are Fate- and Function-Dependent

Andrew E. Ekpenyong, G. Whyte, K. Chalut, S. Pagliara, F. Lautenschläger, C. Fiddler, S. Paschke, U. Keyser, E. Chilvers, J. Guck

PLoS ONE, 2012

Quantitative analysis of deformability-based cell separation using deterministic lateral displacement and optical stretching

D. Holmes, G. Whyte, Andrew E. Ekpenyong, J. Guck, T. Duke

2012

Quantifying cellular differentiation by physical phenotype using digital holographic microscopy.

K. Chalut, Andrew E. Ekpenyong, Warren L Clegg, Isabel C Melhuish, J. Guck

Integrative Biology, 2012

Chromatin decondensation and nuclear softening accompany Nanog downregulation in embryonic stem cells.

K. Chalut, Markus Höpfler, F. Lautenschläger, Lars Boyde, C. J. Chan, Andrew E. Ekpenyong, A. Martinez-Arias, J. Guck

Biophysical Journal, 2012

Comparison of stresses on homogeneous spheroids in the optical stretcher computed with geometrical optics and generalized Lorenz-Mie theory.

Lars Boyde, Andrew E. Ekpenyong, G. Whyte, J. Guck

Applied Optics, 2012

Quantitative imaging for assessing physical phenotypes in stem cells

K. Chalut, Andrew E. Ekpenyong, J. Guck

2011

Dual-beam laser traps in biology and medicine: when one beam is not enough

G. Whyte, F. Lautenschläger, M. Kreysing, Lars Boyde, Andrew E. Ekpenyong, U. Delabre, K. Chalut, K. Franze, J. Guck

NanoScience + Engineering, 2010

Diffraction Imaging Flow Cytometric and 3D Morphological Analysis of Three Cell Lines

K. Jacobs, Junhua Ding, Li V. Yang, Carissa L. Reynolds, Andrew E. Ekpenyong, Yuanming Feng, M. Farwell, Jun Q. Lu, Xin-Hua Hu

2010

Determination of cell elasticity through hybrid ray optics and continuum mechanics modeling of cell deformation in the optical stretcher.

Andrew E. Ekpenyong, Carolyn L. Posey, Joy L. Chaput, Anya K Burkart, Meg M. Marquardt, Timothy J. Smith, M. Nichols

Applied Optics, 2009

Study of 3D cell morphology and effect on light scattering distribution

Andrew E. Ekpenyong, Junhua Ding, Li V. Yang, N. Leffler, Jun Q. Lu, R. S. Brock, Xin-Hua Hu

European Conference on Biomedical Optics, 2009

Diffraction imaging of spheres and melanoma cells with a microscope objective

K. Jacobs, Li V. Yang, Junhua Ding, Andrew E. Ekpenyong, R. Castellone, Jun Q. Lu, Xin-Hua Hu

Journal of Biophotonics, 2009

Hybrid Ray Optics and Continuum Mechanics Modeling of Cell Deformation in the Optical Stretcher

Andrew E. Ekpenyong, M. Nichols

2007