Journal article
K. Jacobs, Li V. Yang, Junhua Ding, Andrew E. Ekpenyong, R. Castellone, Jun Q. Lu, Xin-Hua Hu
Journal of Biophotonics, 2009
Journal of Biophotonics, 2009
Semantic Scholar
DOI
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APA
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Jacobs, K., Yang, L. V., Ding, J., Ekpenyong, A. E., Castellone, R., Lu, J. Q., & Hu, X.-H. (2009). Diffraction imaging of spheres and melanoma cells with a microscope objective. Journal of Biophotonics.
Chicago/Turabian
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Jacobs, K., Li V. Yang, Junhua Ding, Andrew E. Ekpenyong, R. Castellone, Jun Q. Lu, and Xin-Hua Hu. “Diffraction Imaging of Spheres and Melanoma Cells with a Microscope Objective.” Journal of Biophotonics (2009).
MLA
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Jacobs, K., et al. “Diffraction Imaging of Spheres and Melanoma Cells with a Microscope Objective.” Journal of Biophotonics, 2009.
BibTeX Click to copy
@article{k2009a,
title = {Diffraction imaging of spheres and melanoma cells with a microscope objective},
year = {2009},
journal = {Journal of Biophotonics},
author = {Jacobs, K. and Yang, Li V. and Ding, Junhua and Ekpenyong, Andrew E. and Castellone, R. and Lu, Jun Q. and Hu, Xin-Hua}
}
Abstract
Diffraction imaging of polystyrene spheres and B16F10 mouse melanoma cells embedded in gel has been investigated with a microscope objective. The diffraction images acquired with the objective from a sphere have been shown to be comparable to the Mie theory based projection images of the scattered light if the objective is translated to defocused positions towards the sphere. Using a confocal imaging based method to reconstruct and analyze the 3D structure, we demonstrated that genetic modifications in these cells can induce morphological changes and the modified cells can be used as an experimental model for study of the correlation between 3D morphology features and diffraction image data. (© 2009 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
