Dr Andrew E. Ekpenyong

Associate Professor of Physics. BPhil (Rome), BD (Rome), MS (Physics, Creighton, USA), PhD (Physics, Cambridge, UK)



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Dr Andrew Edet Ekpenyong

Associate Professor of Physics


Curriculum vitae



Office Phone: +14022802208


Physics

Creighton University

2500 California Plaza,
Omaha,
NE 68178,
USA




Dr Andrew E. Ekpenyong

Associate Professor of Physics. BPhil (Rome), BD (Rome), MS (Physics, Creighton, USA), PhD (Physics, Cambridge, UK)



Office Phone: +14022802208


Physics

Creighton University

2500 California Plaza,
Omaha,
NE 68178,
USA



Diffraction imaging of spheres and melanoma cells with a microscope objective


Journal article


K. Jacobs, Li V. Yang, Junhua Ding, Andrew E. Ekpenyong, R. Castellone, Jun Q. Lu, Xin-Hua Hu
Journal of Biophotonics, 2009

Semantic Scholar DOI PubMed
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Cite

APA   Click to copy
Jacobs, K., Yang, L. V., Ding, J., Ekpenyong, A. E., Castellone, R., Lu, J. Q., & Hu, X.-H. (2009). Diffraction imaging of spheres and melanoma cells with a microscope objective. Journal of Biophotonics.


Chicago/Turabian   Click to copy
Jacobs, K., Li V. Yang, Junhua Ding, Andrew E. Ekpenyong, R. Castellone, Jun Q. Lu, and Xin-Hua Hu. “Diffraction Imaging of Spheres and Melanoma Cells with a Microscope Objective.” Journal of Biophotonics (2009).


MLA   Click to copy
Jacobs, K., et al. “Diffraction Imaging of Spheres and Melanoma Cells with a Microscope Objective.” Journal of Biophotonics, 2009.


BibTeX   Click to copy

@article{k2009a,
  title = {Diffraction imaging of spheres and melanoma cells with a microscope objective},
  year = {2009},
  journal = {Journal of Biophotonics},
  author = {Jacobs, K. and Yang, Li V. and Ding, Junhua and Ekpenyong, Andrew E. and Castellone, R. and Lu, Jun Q. and Hu, Xin-Hua}
}

Abstract

Diffraction imaging of polystyrene spheres and B16F10 mouse melanoma cells embedded in gel has been investigated with a microscope objective. The diffraction images acquired with the objective from a sphere have been shown to be comparable to the Mie theory based projection images of the scattered light if the objective is translated to defocused positions towards the sphere. Using a confocal imaging based method to reconstruct and analyze the 3D structure, we demonstrated that genetic modifications in these cells can induce morphological changes and the modified cells can be used as an experimental model for study of the correlation between 3D morphology features and diffraction image data. (© 2009 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)


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